However, just 15% of H3K27me3 peaks in WT cells had been bought at genomic areas with CGIs, a genomic element regarded as crucial for initial recruitment of PRC2,44-46 whereas the percentage of peaks with CGIs can be fairly high (45%) in PHF19-KD cells because of disproportional lack of H3K27me3 at non-CGI areas (Figure 4H; also see black bars for CGIs in Figure supplemental and 4F-G Figure 4C-E)

However, just 15% of H3K27me3 peaks in WT cells had been bought at genomic areas with CGIs, a genomic element […]